English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A high-quality protein substitute,  Hermetia illucens  (black soldier fly) larvae powder, is rich in protein and often used in animal feed. This study aimed to investigate the feasibility and optimal ratio of replacing fish meal with  H. illucens  larvae in weaned piglets and to demonstrate the effects on piglets' growth performance, intestinal microflora and immune performance. Forty-eight female weaned piglets were randomly classified into three groups. Each group consisted of eight pens (replicates), with two piglets per pen. Three groups containing different proportions of  H. illucens  larvae (0, 4, and 8%) were referred to as C, HI4, and HI8. We first designed a 28-day feeding experiment to detect growth performance; after that, the piglets were induced with oral gavage of enterotoxigenic  Escherichia coli  K88 (ETEC K88) and recording diarrhea on day 29 of the experiment. Samples were taken on the 32nd day to detect the effect of  H. illucens  larvae on the immune performance of the weaned piglets.  H. illucens  larvae replacement did not cause any obvious change in the growth performance nether in HI4 nor in HI8 of weaned piglets with 28 d feeding stage.  H. illucens  larvae could improve the intestinal health of weaned piglets by increasing the content of  Lactobacillus  and reducing the content of  Streptococcus . Compared with C+K88 group, the diarrhea rate was attenuated for the  H. illucens  supplemented group. The integrity of ileum villi in HI4+K88 and HI8+K88 groups was better than that in C+K88 group, and the villi in C+K88 group were severely damaged. The expression of  IL-10, Occludin  and  Claudin-3  in the intestinal mucosa of the HI4+K88 group and HI8+K88 group were significantly increased ( P  &amp;lt; 0.05), and the expression of  TNF -α was significantly decreased ( P  &amp;lt; 0.05) compared with the C+K88 group. The results of immunoblotting also validated that the same ETEC K88 treatment of weaned piglets enhanced the expression of tight junction protein in the intestinal mucosa of the  H. illucens  addition group. ETEC-induced diarrhea will be reduced by the diet of weaned piglets containing  H. illucens  larvae, ameliorating the immune performance of piglets. Our results indicates that the optimal dosage of  H. illucens  replacement in weaned piglets is 4%.

frontiers in veterinary science

Dietary Hermetia illucens Larvae Replacement Alleviates Diarrhea and Improves Intestinal Barrier Function in Weaned Piglets Challenged With Enterotoxigenic Escherichia coli K88