English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Campylobacter jejuni  is one of the leading causes of gastrointestinal illness worldwide and is mainly transmitted from chicken through the food chain. Previous studies have provided increasing evidence that this pathogen can colonize and replicate in broiler chicken during its breeding; however, its temporal kinetics in laying hen are poorly understood. Considering the possible interaction between  C. jejuni  and gut microbiota, the current study was conducted to address the temporal dynamics of  C. jejuni  in the cecum of laying hen over 40 weeks, with possible alteration of the gut microbiota and fatty acid (FA) components. Following oral infection with  C. jejuni  81-176, inocula were stably recovered from ceca for up to 8 weeks post-infection ( p.i .). From 16 weeks  p.i ., most birds became negative for  C. jejuni  and remained negative up to 40 weeks  p.i . 16S rRNA gene sequencing analyses revealed that most of the altered relative rRNA gene abundances occurred in the order  Clostridiales , in which increased relative rRNA gene abundances were observed at >16 weeks  p.i . in the families  Clostridiaceae, Ruminococcaceae, Lachnospiraceae , and  Peptococcaceae . Lipidome analyses revealed increased levels of sterols associated with bile acid metabolisms in the cecum at 16 and/or 24 weeks  p.i . compared with those detected at 8 weeks  p.i ., suggesting that altered microbiota and bile acid metabolism might underlie the decreased colonization fitness of  C. jejuni  in the gut of laying hens.

frontiers in veterinary science

Long-Term Grow-Out Affects Campylobacter jejuni Colonization Fitness in Coincidence With Altered Microbiota and Lipid Composition in the Cecum of Laying Hens