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Astigmatism is corrected by either by toric lenses or surgical intervention including laser refractive surgery. Photorefractive keratectomy (PRK) is performed with the excimer laser which can accurately ablate corneal tissue to an exact depth with minimal disruption of surrounding tissue, it is done by removing the epithelial layer up to Bowman layer which then ablate with anterior stroma. Laser in situ keratomileusis (LASIK) is also performed with the excimer laser, but with creation a flap involving the stroma. This study aimed to compare the differences in visual outcome after 6 months between PRK and LASIK in treatment of astigmatism. It is a retrospective study in which 222 eyes of 115 patients (some of them had only astigmatism in one eye) who underwent laser refractive correction in Al-Hakeem General Hospital in Annajaf city to correct their astigmatismic refractive error were included in the study, 152 of astigmtismic eyes were corrected by LASIK (82 of female eyes and 70 of male eyes), 67 of astigmatismic eyes were corrected by PRK ( 35 of female eyes and 32 of male eyes). Patients were grouped into six groups according to their refractive error: G1: less than 1.0 dioptre, G2: 1.0-1.9 dioptres, G3: 2.0-2.9dioptres, G4: 3.0-3.9 dioptres, G5: 4.0-4.9dioptres and G6: 5.0-14.0 dioptres. The outcome of visual acuity was followed-up by autorefraction six months postoperatively and were grouped into five groups according to their visual outcome: a:emmetropia, b:no correction, c:undercorrection, d: increase the refractive error, e: overcorrection. The results shows that in those with astigmatism between 0.25-0.9 dioptre, no statistically significant association was found between outcome and type of operation (P=0.66). In those with astigmatism between 1.0-1.9 dioptres, statistically significant association was found between outcome and type of operation (p=0.023). In those with astigmatism between 2.0-2.9 dioptres, statistically significant association was found between outcome and type of operation (P=0.0009). In those with astigmatism between 3.0-3.9 dioptres, statistically significant association was found between outcome and type of operation (P=0.001). In those with astigmatism between 4.0-4.9 dioptres, no statistically significant association was found between outcome and type of operation (P=0.113). In those with astigmatism between 5.0-14.0 dioptres, no statistically significant association was found between outcome and type of operation (P=0.92). In conclusion, there is no statistical significant difference after 6 months of correction of astigmatism wither by LASIK or PRK at different levels of refractive error. Introduction stigmatism is a very common condition that affects the vision of approximately 80% of all people. This condition occurs due to an irregular curvature of the cornea, or front surface of the eye. Astigmatism is often referred to as a refractive error, because the curvature of the cornea causes light to be focused away from its intended target, the retina. This usually causes blurred vision, at all distances, and can be present with other conditions like nearsightedness or farsightedness. The most common symptoms of astigmatism are distortion of A Comparison between PRK and LASIK outcome in myopic astigmatism Raad k yacob & Hashim T AlAmeedy Bas J Surg, December, 20, 2014 47 vision at any distance, headache, fatigue, eye squinting or head tilting. The symptoms of astigmatism can vary in severity. There are some people who have astigmatism that is so mild that they do not require any corrective treatment in order to function normally. Types of Astigmatism: Myopic astigmatism: One or both principal meridians of the eye are nearsighted. (If both meridians are nearsighted, they are myopic in differing degree). Hyperopic astigmatism: One or both principal meridians are farsighted. (If both are farsighted, they are hyperopic in differing degree). Mixed astigmatism: One principal meridian is nearsighted, and the other is farsighted. Astigmatism also is classified as regular or irregular. In regular astigmatism, the principal meridians are 90 degrees apart (perpendicular to each other). In irregular astigmatism, the principal meridians are not perpendicular. Most astigmatism is regular corneal astigmatism, which gives the eye a football shape. Treatment Almost all degrees of astigmatism can be corrected with properly prescribed eyeglasses or contact lenses. For a person with only a slight degree of astigmatism, corrective lenses may not be needed at all, as long as other conditions, such as nearsightedness or farsightedness, are not present. If the astigmatism is moderate to high, however, corrective lenses are probably needed. Corrective lenses (eyeglasses or contact lenses). For astigmatism, special soft contact lenses called toric lenses are prescribed. Soft toric lenses have greater light bending power in one direction than the other. Another option, particularly for higher amounts of astigmatism, is a gas permeable rigid contact lens. After performing various tests, your eye doctor will determine the ideal prescription for your astigmatism. Surgical correction 1.Limbal relaxing incisions/arcuatekeratotomy: involves making paired arcuate incisions on opposite sides of the cornea in the axis of the correcting 'plus' cylinder (the steep meridian). 2. Lens surgery involves using a 'toric' intraocular implant incorporating an astigmatic correction, Postoperative rotation of the implant away from the desired axis occurs in a significant minority. 3. Conductive keratoplasty (CK) involves the application of radio frequency energy to the corneal stroma and can correct low to moderate and hypermetropic astigmatism. Burns are placed in one or two rings in the corneal periphery using a probe. 4. PRK and LASEK. 5. LASIK. Photorefractive keratectomy (PRK) is performed with the excimer laser, which can accurately ablate corneal tissue to an exact depth with minimal disruption of surrounding tissue. Myopia is treated by ablating the central anterior corneal surface so that it becomes flatter; approximately 10/-lm of ablation will correct 1 D of myopia. Hypermetropia is treated by ablation of the periphery so that the centre becomes steeper. PRK is able to correct astigmatism up to 3 D. Technique a. The visual axis is marked and the corneal epithelium removed. b. The patient fixates on the aiming beam of the laser. c. The laser is applied to ablate only Bowman layer and anterior stroma. Comparison between PRK and LASIK outcome in myopic astigmatism Raad k yacob & Hashim T AlAmeedy Bas J Surg, December, 20, 2014 48 The cornea usually heals within 48-72 hours aided by a bandage contact lens. A subepithelial haze invariably develops within 2 weeks and persists for 1-6 months. It rarely causes diminished visual acuity but may give nocturnal glare 1-3 . Complications include slow-healing epithelial defects, corneal haze and haloes, poor night vision and regression of refractive correction. Uncontrol problems include decentred ablation, scarring, abnormal epithelial healing, irregular astigmatism, hypoaesthesia, sterile infiltrates, infection and acute corneal necrosis 1,3-6 . Laser in situ keratomileusis: (LASIK): It is more versatile than PRK and LASEK and can astigmatism of up to 5D. To decrease the risk of subsequent ectasia, a residual corneal base of at least 250 mm thickness must remain after the flap has been cut and tissue ablated. The amount of tissue removed and the total treatment is therefore limited by the original corneal thickness. The thickness of the flap can be varied but thinner flaps are more difficult to handle and more prone to wrinkling 1,7-9 . Technique a. A suction ring is applied to the globe; this raises the intraocular pressure to over 65 mmHg, and may temporarily occlude the central retinal artery and extinguish vision. b. The ring is centred on the cornea and provides a guide track into which an automated microkeratome is inserted. c. The keratome is mechanically advanced across the cornea to create a thin flap, which is reflected. d. Suction is released and the bed is treated with the excimer laser as for PRK. e. The flap is repositioned and allowed to settle undisturbed for 30 seconds. Compared to PRK, the procedure offers the advantages of minimal discomfort, faster visual rehabilitation, rapid stabilization of refraction and minimal stromal haze 1,3,4 . Patients and methods A 222 eyes of 115 patients (some of them had only astigmatism in one eye) who were done a laser refractive correction in Al-Hakeem General hospital in Annajaf city to correct their astigmatismic refractive error were included in this retrospective study. The correction of astigmatismic refractive error correction was done by Nidek machine and all operations were done by the same surgeon. Even that now LASIK become more used than PRK but still there are many indications to perform the PRK in which the surgeon in this study consider the following indications for PRK: Astigmatism (0.75D to 3.0D)-Higher corrections are associated with regression of the effect; therefore, LASIK is the preferred procedure. Patients with documented evidence of a change in manifest refraction of less than or equal to 0.5D (both cylinder and sphere Comparison between PRK and LASIK outcome in myopic astigmatism Raad k yacob & Hashim T AlAmeedy Bas J Surg, December, 20, 2014 49 components) per year for at least 1 year prior to the date of preoperative examination. Patients aged 21 years for the reduction or elimination of myopia from 0D to -6.0 D spherical myopia at the spectacle plane with up to -3.0 D of astigmatism Patients aged 21 years or older with naturally occurring hyperopia from +1.0 D to +4.0 D spherical equivalent, with no more than 1.0 D of refractive astigmatism. PRK in corneas previously treated with LASIK 10,11 . Both PRK and LASIK use excimer laser to ablate the corneal curvature but they differ by that in LASIK

basrah journal of surgery

COMPARISON BETWEEN PHOTOREFRACTIVE KERATECTOMY (PRK) AND LASER IN SITU KERATOMILEUSIS (LASIK) OUTCOME AFTER SIX MONTHS IN TREATMENT OF MYOPIC ASTIGMATISM