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Background: Over the past two decades, there has been global increase in the frequency of dengue fever, dengue hemorrhagic fever and its epidemics, with a concomitant increase in disease incidence. Aim & Objective: The study mainly focuses on the incidence and clinical profile of Dengue fever in Childrens. Methodology: A total number of 500 patients were studied. The study period was from March 2016 to Feb 2018. Sera collected from these patients were tested for the presence of Ig M antibodies and NS1 Ag against Dengue virus. Results: Of the total 500 patients 250 were positive for Ig M antibody, 150 were positive for NS1 Ag against Dengue virus. The prevalence of dengue fever was more common among 3-6 years age group of children. A significant association was found between dengue serology (IgM Antibody & NS1 Ag detection) and complications that are DHF &DSS. A significant association was found between low platelet count and complications that are DHF &DSS. Of the clinical manifestations there was high incidence of pain abdomen, vomiting, arthralgia, body pains, poor intake, facial puffiness and abdominal distention Conclusion: The detection of IgM Antibody & NS1 Ag were valuble in diagnosis of DHF &DSS. Early detection of cases helps in the appropriate control measures and early management of cases. Community participation with emphasis on control measures is very much essential for dengue control. Constant surveillance for dengue viral infection is required to take necessary action by health authorities.

Study on incidence and clinical profile in dengue fever-in tertiary health care center