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Solid pseudopapillary neoplasm (SPN) of the pancreas, first reported by Frantz in 1956, is an uncommon but distinct pancreatic neoplasm with a low malignant potential, accounting for 1–3% of all pancreatic tumors (1). Most SPNs have a tendency to affect young women and have excellent prognoses following complete surgical resection (2). Although the majority of SPNs have an indolent clinical course and low malignant potential, 10% to 15% of cases exhibit aggressive clinical and pathologic features (2). Histologically, most SPNs are composed of uniform polygonal cells with hemorrhage, necrosis, and characteristically prominent cystic portions, but there is a highgrade malignant histologic variant that is composed of numerous nuclear atypia and mitosis, causing a diagnostic dilemma (3). Although there are comprehensive several reports regarding imaging features of SPN in literature, there have been few reports specifying detailed description of diffusion weighted MR imaging findings, including mean apparent diffusion coefficient (ADC) values and normalized ADC values with respect to differentiating SPN with malignant transformation from benign SPN. We herein report a rare case of pancreatic SPN with Imaging Findings of Pancreatic Solid Pseudopapillary Neoplasm with High-Grade Malignant Transformation: Focusing on DiffusionWeighted Imaging and Normalized Apparent Diffusion Coefficient Values       :

daehan yeongsang uihak hoeji/daehan yeongsang ui haghoeji

Imaging Findings of Pancreatic Solid Pseudopapillary Neoplasm with High-Grade Malignant Transformation: Focusing on Diffusion-Weighted Imaging and Normalized Apparent Diffusion Coefficient Values