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Human mesenchymal stem cell (hMSC) is one of minor populated adult stem cells in bone marrow, which can differentiate into adipocytes, chondrocytes, and osteocytes under controlled in vivo and in vitro environments. In comparison to embryonic stem cell, hMSC has advantages of easy isolation and a lesser degree of ethical concern. Based on these advantages, hMSC has been known to be a promising treatment option for various organ diseases and injuries (1, 2). In order to evaluate the effect of stem cell treatment, it is important to investigate the efficacy of stem cell delivery and to trace the route of stem cell migration. Although MRI does not provide the necessary sensitivity and contrast for imaging at cellular level, the endocytosis of magnetic labels allows cells to be tracked and localized (3). The intracellular confinement of suOriginal Article

daehan yeongsang uihak hoeji/daehan yeongsang ui haghoeji

Comparison of Superparamagnetic Iron Oxide Labeling Efficiency between Poly-L-Lysine and Protamine Sulfate for Human Mesenchymal Stem Cells: Quantitative Analysis Using Multi-Echo T2<sup>*</sup>Magnetic Resonance Imaging

Comparison of Superparamagnetic Iron Oxide Labeling Efficiency between Poly-L-Lysine and Protamine Sulfate for Human Mesenchymal Stem Cells: Quantitative Analysis Using Multi-Echo T2*Magnetic Resonance Imaging

Comparison of Superparamagnetic Iron Oxide Labeling Efficiency between Poly-L-Lysine and Protamine Sulfate for Human Mesenchymal Stem Cells: Quantitative Analysis Using Multi-Echo T2^*Magnetic Resonance Imaging