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Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed the role of prostaglandin D 2 (PGD 2 ) signaling in cisplatin-induced neuropathic pain.

Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord

Prostaglandin D₂ contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord