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Background: Although there are many studies that highlight the importance of early resuscitation in severe sepsis, there remains limited or disjointed information about the effect of timely post-resuscitative sepsis management on patient outcomes. Objective: The goal of this descriptive study was to determine if timely implementation of a post-resuscitation sepsis order set (PRSOs) resulted in a decrease in hospital length of stay (LOS) and hospital cost. Methods: In this descriptive study, 749 intensive care unit (ICU) patients were reviewed, 494 (66%) patients received the PRSOs compared to 255 patients who did not. Results: Though not statistically significant, those who received the PRSOs had a decreased hospital length of stay (LOS) by more than one day (9.29 versus 10.33 days) and a decrease in hospital costs ($22,566.54 versus $24,155.98). Conclusion: While the results of this study were not statistically significant, the preliminary results are re-assuring and further study is warranted given the potential implications for future use. *Correspondence: Gilbert Andrew Valasquez, MD., St Joseph’s Medical Center, 2102 N. California Street, Stockton, CA 95204., (619) 3096257. Received: 14 July 2020; Accepted: 11 August 2020

The Effects of Post-Resuscitation Sepsis Management on Length of Stay and Total Cost of Care among Patients with Severe Sepsis in the ICU Setting