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Sumithion is extensively used in the agricultural land to control brittle and larval rearing aquaculture ponds to control tiger bug. The present study was conducted to evaluate the effects of sumithion on blood glucose and hemoglobin levels in zebrafish, Danio rerio . At first acute toxicity (96 h LC50 value 7.89 mg/L) of sumithion was determined for sexually matured zebrafish. Then the fish were exposed to four concentrations (0, 0.5, 1.0 and 2.0 mg/L) of sumithion for a period of 7 days. The sexual dimorphic changes in blood glucose levels were observed in the present study. In male, the blood glucose levels were significantly (P<0.05) increased in all concentrations (0.5, 1.0 and 2.0 mg/L) of sumithion compared to control (0 mg/L), while in female the blood glucose levels were significantly (P<0.05) increased only in high concentration (2.0 mg/L). Interestingly, the blood glucose level was higher in females than the males of zebrafish. The recorded hemoglobin values were significantly decreased with the increasing concentration of sumithion in both male and female. The present investigation revealed the toxic potentiality of sumithion on the zebrafish. Progressive Agriculture 27 (2): 216-221, 2016

Alteration of blood glucose and hemoglobin levels in zebrafish exposed to sumithion