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Background and objective: The objective of this study was to detect the incidence of chorioamnionitis in PPROM and to evaluate the pattern of foetal outcome in these cases at a tertiary care hospital in Bangladesh. This study is also aimed to analyze the influence of the demographic variables predisposing to chorioamnionitis in PPROM in a locality. Materials and Methods: This single centre cross-sectional study was conducted on 110 pregnant women with preterm rupture of membranes at a tertiary care hospital in Dhaka, Bangladesh. The study group was divided according to the presence or absence of clinical chorioamnionitis defined as the presence of two or more of the following criteria: maternal temperature >38°C on two or more occasions ³1 h apart, maternal tachycardia (³120 beats/min), uterine tenderness, foul smelling amniotic fluid, maternal leukocytosis ³20,000 mm –3 with bands and positive C reactive protein. Antibiotics and tocolysis were used according to the hospital protocols. Foetal outcome was measured on the basis of weight of the baby, and presence of infection (fever), Apgar score and neonatal death. Analysis was performed using SPSS-12. Results: In this study the rate of chorioamnionitis in PPROM was 25.4%.The chorioamnionitis was found to be frequent (57.1%) in younger age group between 15–25 years while PPROM without chorioamnionitis was common (53.6%) among the age group between 26–35 years. Lower socioeconomic class and history of previous PROM and DC Vol. 26(1) : 10-19

bangladesh journal of obstetrics and gynaecology

The Incidence, Risk Factors and Common Foetal outcome of Chorioamnionitis in Women with Preterm Premature Rupture of Membrane (PPROM): A Single Centre Study