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Genetic alterations of the mixed lineage leukemia 1 gene ( MLL1 , here referred to as MLL ) located on the long arm of chromosome 11 (11q23) are found in pediatric (particularly infant) and about 5–10% of adult de novo and therapy-related acute lymphoblastic leukemias (ALL) or acute myeloblastic

Trithorax and polycomb cooperation in MLL fusion acute leukemia