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Following on from recent studies which suggest in patients over 50 years of age an age-dependent D-dimer cut off of ‘age multiplied by 10’, in conjunction with a non-high clinical probability, can be used to safely exclude pulmonary embolism (PE),[1][1]-[3][2] we read with interest the

haematologica

The use of age-dependent D-dimer cut-off values to exclude deep vein thrombosis. Reply to "Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded". Haematologica 2012;97(10):1507-13