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Methylation of DNA in CpG-rich islands is a key event in the regulation of tissue- and context-specific gene expression. Thereby, DNA methyltransferase 3A ( DNMT3A ) plays a pivotal role by converting cytosine to 5-methylcytosine.[1][1] Recently, DNMT3A mutations have been described at high

Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia