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Primary light chain (AL) amyloidosis, the commonest type of amyloidosis, presents with cardiac involvement in 50% of patients. Cardiac amyloidosis causes a restrictive cardiomyopathy and is the major determinant of treatment related toxicity and death.[1][1] Echocardiography remains the gold

haematologica

Abnormal N-terminal fragment of brain natriuretic peptide in patients with light chain amyloidosis without cardiac involvement at presentation is a risk factor for development of cardiac amyloidosis