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Food -protein induced proctocolitis is a non -IgE mediated hypersensitivity reaction, most often triggered by the ingestion of cow’s or soy milk but it has also been recognized in exclusive breastfed infants. It may occur in the f irst weeks of life and its diagnosis is challenging given the lack of specif icity of clinical manifestations, often leading to invasive and unnecessary medical interventions. Clinical report: The authors present a one -month old infant, exclusively breastfed, admitted for bloody stools, irritability and declining oral intake, whose clinical investigation was consecutively negative and whose clinical manifestations reversed after excluding breast milk eviction and introducing of extensively hydrolyzed milk. Conclusions: The exclusion of the triggering food protein usually leads to complete clinical response and no late sequelae. It may be necessary to stop breastfeeding in infants in whom no other cause for hypersensitivity has been identif ied.

Proctocolite induzida por proteína alimentar em lactente sob aleitamento materno exclusivo