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This study evaluated the compound hydroxyapatite-lignin as an osseous-integrator between bone tissue and a metal implant, using a traction test. The research was considered opportune, due to the necessity to discover a biomaterial, which guides and has chemical and mechanical properties similar to the bone, in order to replace the methyl methacrylate used in the stem joint fixation of prosthesis. 20 New Zealand rabbits were employed; in all of them the left tibia was treated with the compound and, the not treated right tibia was considered the control. A bone fail, 4mm in diameter, was performed in the proximal lateral tibial surface, up to the marrow channel. 1000mg of the compound were softened with ten drops of NaCl (0.9%) using part of the dough used to coat the thread of the intra-marrow Schanz steel nail for cortical bone, diameter 2.5mm. The other part was entered into the spinal channel of the treated group, with the help of a caliber 16-gauge catheter and a syringe. Afterwards, 7cm of the nail were introduced into the marrow channel. The affected anatomic parts were sutured. The same was executed with the control group, without the use of the compound. The assessments were performed 8, 30, 60, 90 and 120 days post surgery. In the traction test no statistical differences between treated and control group were observed, despite that in the first group, the result was double the resistance strength than that of the control. Based on the results it is concluded that the lignin-hydroxyapatite compound facilitates the osseous-integration of the intra-marrow nail.

Compuesto de hidroxiapatita-lignina como óseo-integrador entre tejido óseo e implante metálico: evaluación mecánica