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ABSTRACT The primary aim of this randomized study is to find the effect of a diet based intervention (vegan diet and low-calorie diet) among women suffering from polycystic ovary syndrome (PCOS). Overweight and obese (BMI- 33.7 ± 4.8 kg/m2) women with PCOS (n = 21; age, 33.1 ± 4.4 years) were assessed to participate in a 90 days randomized weight loss study delivered and guided through diet and nutrition counseling (personalized and group). Body weight, BMI and waist circumference and dietary intakes were assessed three times at 0, 45 and 90 days. It was hypothesized that weight loss would be more in the vegan group. All data were statistically analyzed and presented as median (inter quartile range). Vegan participants reported significant weight loss at Day 90, “1.8% (“5.0%, “0.9%) vegan, 0.0% (“1.2%, 0.3%) low-cal; P = .04), Vegan participants showed a greater decrease in energy (“265 (“469, 0)) kcal/d) and fat intake “8.2% (“9.8%, 0%) energy) at Day 90 compared with low-cal participants (0 (0, 173)) kcal/d, P = .02; 0 (0, 3.7%) energy, P = .02). The results suggest that following a vegan diet can be more effective for achieving weight loss in addition to better nutrient intake profile in women with PCOS; however, a bigger sample size is required to validate these results.

Vegan or Low Calorie Diet for Weight Loss in Polycystic Ovary Syndrome Females: A Randomised Controlled Study