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Objective: The aim of this study was to examine the relationship between depression and demographic and clinical characteristics of the patients, and the effects of depression on quality of life (QoL) in patients within the first six months after spinal cord injury (SCI). Material and Methods: One hundred patients with traumatic SCI who underwent inpatient rehabilitation program were enrolled in the study. Demographic data, etiology of injury and duration of disease (days) were recorded for all patients. Neurological level (cervical, thoracal, lumbosacral) and lesion severity (complete, incomplete) were determined according to the American Spinal Injury Association Impairment Scale (AIS). The Functional Independence Measure was used to assess functionality, the 36-Item Short-Form Health Survey was used to evaluate QoL, and the Beck Depression Inventory was used to assess depression. Results: There was a relationship between depression and female gender, lower education level, type of caregiver, the presence of pain and sleep disturbances. No relation was found between depression and injury severity, level of injury, or extent of functional impairment. BDI scores were negatively correlated with most of the components of SF-36 quality of life scale. There was a statistically significant difference in SF 36-Mental Component Scores between the groups according to the depression severity. Cared by a foreign caretaker, having a sleep disturbance and pain were found to be associated independent risk factors with the presence of clinically significant depression. Conclusion: The results of this study demonstrate that gender, education level, type of caregiver, presence of pain and sleep disturbances are the major determinants of depression in patients within the first six months after SCI. Findings showed the importance of family support to care for patients in SCI rehabilitation. It is important to treat pain, sleep disturbance and depression together in an early period of rehabilitation to improve QoL.

The Impact of Depression on Quality of Life and Depression Related Factors in Patients with Spinal Cord Injury