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Animal health is a major concern in today’s livestock industry. Not only is animal illness costly, but it also affects all aspects of the industry from the cow calf producer to the feedlot operator. Bovine respiratory disease (BRD) has large economic ramifications to the beef industry. Bovine respiratory disease has been characterized an interaction between environment, stress, and infectious pathogens. Preventative methods such as vaccination have been used to minimize the repercussions that have been associated with BRD. While vaccination has been used as a preventative method, it is only effective if an immune response is mounted to the specific antigen present in the vaccine. The objectives of the studies were three fold: 1) to identify sources of fixed effects that influence maternal antibody levels and maternal antibody decay, 2) to identify the environmental and management factors that influence antibody response to BVDV2 vaccine, and 3) to evaluate effects of BVDV2 antibody response on body composition ultrasound, performance, and carcass quality traits. In these studies, immune response was measured by antibody response to bovine viral diarrhea virus type 2 (BVDV2). With respect to objectives 1 and 2: calf age nested within birth year season and dam age significantly (P<0.05) affected all passively-acquired maternal antibody level and vaccine response traits evaluated. The amount of circulating passively-acquired maternal antibodies present at the time of vaccination has a significant (P<0.05) effect on antibody response to vaccination for final antibody level and initial, booster, and overall response. Calves that were weaned at the initial vaccination had significantly (P<0.05) higher final antibody levels and response to vaccination compared to animals weaned at the booster

Evaluation of environmental effects on bovine viral diarrhea virus type 2 (BVDV2) antibody levels and response to BVDV2 vaccinations in Angus calves