English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Giant cell tumour (GCT) is histopathologically benign tumor of long bone particularly in distal femur and the proximal tibia. It commonly occurs in adults of age 20-40 years but rare in children. GCT is considered to be locally aggressive tumor and tendency of recurrence is higher even after surgery. The clinical features are nonspecific, the principle symptoms are pain, swelling and limiting adjacent joint movements. Diagnosis is based on the radiographic appearance and histopathological findings .In our case X-ray showed ill defined lytic lesion on proximal fibula with cortical thinning and MRI finding revealed expansile lytic lesion in meta-epiphysis of right fibula 16×16×28mm adjacent to growth plate with fluid level. The sclerotic rim appears hypointense on T1 & hyperintense on T2. Core needle biopsy showed giant cell tumor on proximal fibula. Considering the risk of recurrence wide local excision was done. Management of GCT of proximal fibula in young patient is critical for preventing recurrence and enhancing functional outcomes by saving adjacent anatomical structure. No evidence of local recurrence and metastasis was found in 24 months of follow up. Introduction Histopathologically Giant cell tumor (GCT) is a common benign tumor of long bone. It is classified as osteoclastic gaint cell rich tumors of intermediate grade with local aggressiveness and capacity to metastasize. GCT commonly occurs in mature skeleton. The incidence of occurrence lies between age 20 to 40 years but rare in children.1-3 The common sites for GCT in long bone are distal femur and proximal tibia.4-5 Literatures showed that GCT in the immature skeleton varies from 1.8% to 10.6%.6 A retrospective study conducted in GCT by Strom et.al in Oslo, Norway from 1984-2015 found that out of 154 patients 89% were more than 15 years. This finding reveled that GCT is more in mature skeleton than in immature skeleton. The biological characteristics, symptom and treatment of the tumor in children do not differ from the adults.7-8 The principal symptoms are pain and swelling around affected joints followed by limited movements and sometimes presents with pathological fractures. The definitive diagnosis is based on radiographic and histopathological finding. Universally surgery is primary treatment for GCT. Commonly practicing surgical treatment are extended currattage with through the use of power burr, Phenol, liquid nitrogen, bone cement, hydrogen peroxide, zinc chloride and argon beam cauterization. Selection of appropriate surgical treatments plays a vital role in reducing recurrence rate for functional as well as oncological outcomes. Case report Seven years boy came to the BPKMCH with the features

A Case Report of Giant Cell Tumor of Proximal Fibula in Children