Open AccessManagement of Epidermoid Carcinoma of the Anus
Author(s) -
Lars Påhlman,
Bengt Glimelius,
Sven Goldman
Publication year - 1988
Publication title -
upsala journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.808
H-Index - 41
eISSN - 2000-1967
pISSN - 0300-9734
DOI - 10.3109/03009738809178542
Subject(s) - medicine , anus , epidermoid carcinoma , treatment modality , carcinoma , primary treatment , anal carcinoma , surgery , anus neoplasms , disease , anal canal , general surgery , rectum
In two unselected, consecutive and population-based patient materials from two regions in Sweden, different treatment modalities in patients with epidermoid carcinoma of the anus have been evaluated. By using a primary radiotherapeutic approach, combined with surgery in patients with large and/or less radiosensitive tumours, considerably more surviving patients can be disease-free in the long term compared with a primarily surgical approach. In addition, several patients will have preserved anal function. Based upon these data together with the experience described in the literature, we conclude that surgery is no longer the primary treatment of choice in patients with anal carcinoma.