Open AccessThe Application of Two-dimensional Centrifugation to Clinical Chemistry Testing
Author(s) -
J T Holen,
Steven G. Schultz,
Sie Ting Wong
Publication year - 1986
Publication title -
upsala journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.808
H-Index - 41
eISSN - 2000-1967
pISSN - 0300-9734
DOI - 10.3109/03009738609178506
Subject(s) - spectrum analyzer , reagent , centrifugation , analyte , chromatography , medicine , analytical chemistry (journal) , biomedical engineering , chemistry , optics , organic chemistry , physics
We have developed a new clinical chemistry analyzer, the VISION System, which uses centrifugal force to separate whole blood, measure reagent and plasma volumes, and complete all steps required for a spectrophotometric analysis. The system is based on a multichambered test pack containing liquid reagents, which can be centrifuged in two planes oriented at right angles to each other. The analyzer regulates the temperature, timing and optical measurements for up to 10 different test packs in the same run. We have demonstrated good precision and accuracy on 6 clinical chemistry analytes, 2 enzymes, potassium and theophylline using this system.