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This study aimed to implement Project Based Learning (PjBL) model to improve creative thinking skills of students in class XI of SMK Farmasi ISFI Banjarmasin. The method used in this research was quasi-experiment with pretest-posttest control group design. The subjects were students of class XI SMK Farmasi ISFI Banjarmasin consisting of 70 students. The data were analyzed by Anacova with pretest as covariate. Then, the students’ responses on project based learning model were also investigated during the implementation of the model. This research instruments were interview, documentation and tests. The results of the data analysis showed that the significant values was 0.000 from pretest, posttest and corrected model. Students’ critical thinking skills were improved using Project Based Learning (PjBL) in class XI SMK FARMASI ISFI Banjarmasin.

Improving Creative Thinking Skills by Implementing Project Based Learning on Human Organ System Material