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Methods: Low Flow Mediated Constriction (LFMC) and Flow Mediated Dilation (FMD) were measured to evaluate ‘resting’ and ‘recruitable’ endothelial function as change in diameter of the brachial artery (ΔD) during and after 5 minutes of suprasystolic occlusion of the forearm in comparison to baseline artery diameter using B-mode ultrasound (M7, MindRay) in 27 healthy subjects (Age 50.8 ± 9.6 years). Central and peripheral regional arterial stiffness was assessed using applanation tonometry (SphygmocorÒ) to calculate carotid-femoral(cf) and carotid-radial(cr) Pulse Wave Velocity (PWV) respectively.

2.5 Differential Association of Central and Peripheral Arterial Compliance with Resting and Recruitable Endothelial Function in Healthy Human Subjects