English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Objectives: Isolation and Identification of S.aureus and study their susceptibility to the production of virulence factors. * Methods: A total 50 clinical specimens of Staphylococcus aureus isolates were collected in ALNajaf ALAsharaf governorate during the period of (10/10/2013-20/1/2014) by the cultural characteristic colonies, microscopic for cells, biochemical tests, antibiotics susceptibility test to Staphylococcus aureus using an antibiotic diffusion disc assay, in addition to studying the virulence factors produced from S.aureus . * Results: The results show that the Staphylococcus aureus resistant to methicillin formed 70% and 30% of isolates were sensitive to the same antibiotics. Tested 10 isolates to methicillin resistant for their efficiency in forming the highest inhibitory areas for testing their sensitivity to other antibiotics used, the results show S.aureus resistant to penicillin about 100%, while there is no resistance to CO-Trimethoprim because it was sensitive completly 100%. The susceptibility investigated of Staphylococcus aureus resistance methicillin isolates to the production of biofilm and slime layer with using both tube method and growth on Congo red agar respectively. Ten isolates of S.aureus were tested based on resistance to methicillin and their high susceptibility to the production of the biofilm and the slime layer. * Conclusion: So we conclusion, they have Staphylococcus aureus is highly resistant to βLactam antibiotics and the CO-trimethoprim is the most effective in the inhibiting growth of this bacteria. In addition to its ability to produce virulence factors. The increase cause bacterial resistance to our local isolates may be due to the frequent use of antibiotics, which allowed for increased bacterial resistance to various antibiotics. 1-Introduction:In recent years, there has been an alarming increase in hospital-related infections caused by multidrugresistant Staphylococcus strains, Shown some strains have no resistance to more than 20 antibacterial compounds, including antiseptics[1]. Staphylococcus aureus is one of the most important pathogens that is capable of causing various types of infections at multisite in human body, The pathogenesis is linked to its ability to produce many virulence factors, which include the production of toxins, extracellular enzymes and other factors, which gives bacteria the ability to multiply and spread within host tissues as well as the high resistance and multiple antibiotics, especially belonging to the group βLactam and aminoglycoside, making it a major pathogen causing hospitalnosocomial infection [2]. And that the transmittability of antimicrobial resistance between bacterial strains is a health problem, including resistance to vancomycin, which is used as an alternative to beta-lactam antibodies to gram-positive bacteria treated, particularly S.aureus [3]. Methicillin Resistance Staphylococcus aureus (MRSA) has also caused many diseases, including endocarditis and chronic osteoarthritis [4]. Although, MRSA has many mechanisms to increase pathogenicity and virulence, including biofilm production and host cell adhesion [5]. Journal of University of Babylon for Pure and Applied Sciences (JUBAS) by University of Babylon is licened under a Creative Commons Attribution 4.0 International License. 2018.

Isolation and Identification of Methicillin Resistance Staphylococcus aureus and Detection their Ability to the Production of Virulence Factors