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This article searches for biological urogenital tract markers on the urothelium hyperfunction model in systemic atherosclerosis. We revealed the main parameters of pathological aging of urogenital tract. We have obtained the data that the pathological aging of urogenital tract is characterized by a significant increase in the acetylcholine expression from 0.52 to 0.82 cu, glutamate from 0.53 to 0.83 cu, beta-1 transforming growth factor from 0.452 to 0.497 ng/ml and a decrease in the levels of optical expression area in serotonin urothelium from 0.43 to 0.36 cu and dopamine from 0.42 to 0.35 cu. Within the framework of this article, we have proved that the indicators of urothelium expression of acetylcholine, glutamate, beta-1 transforming growth factor (an increase of their expression indicates pathological aging), the urothelium expression rates of serotonin and dopamine (a decrease in their expression indicates pathological aging) can be used as the biological markers of the pathological aging of urogenital tract on the combination model of urothelium hyperfunction and systemic atherosclerosis.

Biological Markers of Pathological Aging in Diseases of Men