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Objective. To establish the efficacy of transurethral resection of prostatic gland (TURPG) in patients, suffering prostatic intraepithelial neoplasia (PIN) of central zone. Маterials and methods. Results of treatment of 72 patients, suffering benign hyperplasia of prostatic gland Stages І–ІІІ and PIN of central zone, are adduced. Depending on the treatment tactic applied, the patients were divided into 3 Groups: dynamical follow–up (Group 1), medicinal therapy, using dutasterid (Group 2), and TURPG (Group 3). Follow–up period have constituted 3 years. Results. Among the patients, suffering PIN of the prostatic gland central zone, prostatic gland cancer (PGC) was revealed in 15 (20,8%). In the treatment absence, the PGC occurrence rate have constituted 42,9%. At the same time the pancreatic gland adenocarcinoma after ТURPG during follow–up period was not revealed. Conclusion. Оperative intervention, using TURPG, constitutes an effective prophylactic method for the PIN malignant transformation. Treatment of patients, suffering PIN, is directed to prophylaxis of the PGC occurrence.

The role of transurethral resection of prostatic gland in treatment of prostatic іntraepithelial neoplasia