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Early detection and treatment of white spot lesions (WSL) is pivotal in caries control. Several commercially available products are available for WSL reversal. However, themajority of them are either synthetically derived or are not a hundred percent ef icient. Thus there is an ever constant need to ind newer, more ef icacious products for the same. One of the parameters to quantify de and remineralization is by Quantitative Light Induced Fluorescence (QLF). Thus this study aims to evaluate and compare the remineralizing potential of Zingiber of icinale Roscoe (Ginger rhizome), Apis Mellifera (Manuka Honey) mixture and chitosan on arti icial demineralized human enamel using Quantitative Light Induced Fluorescence. 45 human enamel samples were randomly divided into a control and two test groups. An Area of Interest (AOI) measuring 4x4 mm on the buccal surface of each tooth was formed and all the samples were subjected to demineralization process for a period of 96 hours. Remineralization regime was then carried out with twice daily application of respective interventional agents for a period of 21 days. QLF readings were recorded at the end of demineralization (Baseline), Day 7, Day 14 and Day 21 and luorescence imageswere analysed using QLF InpektorTMpropriety software. The remineralization action of chitosanwas found to be the highestwith a statistically signi icant reduction (p<0.001) seen at the end of 7th, 14th and 21st day. Gingerhoney mixture also showed reduction in luorescence levels but only after the 14th day. The current study showcases the dramatic ability of chitosan to almost completely reverse arti icially formed WSL at each subsequent week. Ginger honey on the other hand showed a signi icant remineralization between2nd and3rdweekwhichmaybe attributed to a possible slower mechanism of action.

international journal of research in pharmaceutical sciences

Evaluation of Remineralisation Potential of Zingiber officinale Roscoe-Apis Mellifera, and Chitosan as compared to control using QLF on white spot lesions: An in-vitro study