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To evaluate the efficacy of laser-assisted vascular anastomosis (LAVA) for the wound healing, collagen content, non-collagenous protein content and collagen concentration were measured at 1 hour and 7, 15, 30, 60 and 90 days after anastomosis of canine common carotid artery . The dye-binding method was employed, Results were compared to conventional suture vascular anastomosis (CSVA) with 7-0 polypropyrene. In LAVAs, collagen content and conecntration rapidly increased and hit a peak at 15 days, then, after 30 days, returned to the same value as at 1 hour. In CSVA, they were gradually increased and maintained high level even 130 days after surgery . 第14巻 第2号1993年6月 日本 レーザー医学会誌 31 From these results, we concluded that LAVAs gained better and more rapid healing than CSVAs.

Wound healing of laser-assisted vascular anastomosis from the viewpoint of tissue collagen dynamics