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Post-treatment hypothyroidism is common in Graves' disease, and clinical guidelines recommend monitoring for it; however, thyroid stimulating hormone (TSH) can remain suppressed in these patients following treatment. The objectives of this study were to explore the proposed pathophysiology behind the phenomenon of post-therapy TSH suppression and to systematically review existing clinical data on post-therapy TSH suppression in patients with Graves' disease.

Thyroid Stimulating Hormone Suppression Post-Therapy in Patients with Graves’ Disease: A Systematic Review of Pathophysiology and Clinical Data