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The role of vitamin D in obesity is still pros and cons among scientists. The association between obesity and low concentration of 25 (OH) D3 appears to be very clear, although the mechanisms regarding low concentrations of (OH) D3 are still unclear, as the consequences of low levels of 25 (OH) D3. The purpose of this paper is to find out how vitamin D metabolism in obese people, that explain the factors that lead to vitamin D deficiency in obesity. Literature study is used to review the article about vitamin D deficiency in obesity which published from 2010-2017. There are two theories that explain low levels of vitamin D in obese people: sequestration theory and degradation theory. Sequestration Theory: states that obese individuals experience failure to convert pre-vitamin D to vitamin D in their skin tissue, where excess fatty tissue can sequester fat-soluble vitamins so that serum 25 (OH) D3 levels become low. Degradation Theory is states that the amount of fatty tissue will stimulate infiltration of activated immune cells that cause adipose tissue inflammation and degradation of vitamin D that make decreasing on vitamin D levels in obese cases. The conclusion is obesity was associated with low levels of vitamin D and sequestration theory also degradation theory explain low level of vitamin D in obese people.

sport and fitness journal

PERBANDINGAN EFEKTIVITAS KONTRAKSI (25%, 50% DAN 75%) DARI NILAI KONTRAKSI MAKSIMAL PADA TEKNIK CONTRACT RELAX TERHADAP PENINGKATAN FLEKSIBILITAS OTOT HAMSTRING