English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Pimavanserin (Nuplazid) is the first FDA atypical antipsychotic drug approved for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis (PDP). Pimavanserin displays a unique pharmacological profile with nanomolar potency as a 5-HT2A receptor inverse agonist. Due to the importance of Pimavanserin for the field of neurological disorder, numerous reports have appeared in the literature dealing with the synthesis of Pimavanserin. In this article we collect, summarize and discuss the various synthetic strategies and judge their applicability for larger scale drug synthesis.

Methods of synthesis of Pimavanserin: the first drug approved for the treatment of Parkinson's disease psychosis (PDP)