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Characteristics of Cardiovascular Risk Factors and Their Correlation with the Sex and Age of Patients in the Latvian Population Various cardiovascular risk factors (RFs) were determined in 773 out-patients (mean age 55.8 ± 14.5 years). Male individuals had a larger waist circumference (WC) than did female patients (99.1 ± 13.6 cm vs 93.3 ± 15.2 cm), higher diastolic blood pressure (DBP) (83.6 ± 9.6 mmHg vs 81.8 ± 9.6 mmHg), and higher levels of blood glucose (5.73 ± 1.4 mmol/L vs 5.49 ± 1.3 mmol/L) and triglycerides (TG) (1.89 ± 1.3 mmol/L vs 1.60 ± 1.0 mmol/L), but lower levels of total cholesterol (TC) (5.54 ± 1.2 mmol/L vs 5.79 ± 1.2 mmol/L) and high-density lipoprotein cholesterol (HDL-C) (1.21 ± 0.4 mmol/L vs 1.44 ± 0.4 mmol/L). Compared with the younger age group (i.e., males, < 7 years; females, < 65 years), patients in the older age group had a larger WC (98.4 ± 14.2 cm vs 92.8 ± 15.1 cm), higher systolic blood pressure (SBP) (144.2 ± 19.2 mmHg vs 131.6 ± 18.5 mmHg), higher DBP (84.5 ± 8.8 mmHg vs 80.9 ± 9.8 mmHg), higher blood glucose level (5.74 ± 1.3 mmol/L vs 5.46 ± 1.3 mmol/L), and higher low-density lipoprotein cholesterol level (LDL-C) (3.68 ± 1.0 mmol/L vs 3.52 ± 1.0 mmol/L), but lower HDL-C level (1.3 ± 0.4 mmol/L vs 1.41 ± 0.4 mmol/L). Age was significantly correlated with all RFs, with the exception of the level of C-reactive protein. In conclusion, analysis of cardiovascular RFs in different age subgroups of both sexes clearly showed individual peculiarities of risk profile. This conclusion challenges the usual way of risk calculation using "universal" markers like adiposity or dyslipidemia in all population. The new approach requires individual attention depending on sex and age also in management of risk. Kardiovaskulārie Riska Faktori un to Korelācija Ar Pacientu Dzimumu un Vecumu Latvijā 773 ambulatoriem pacientiem (ar vidējo vecumu 55,8 ± 14,5 gadi) tika analizēti dažādi sirds asinsvadu slimību (SAS) riska faktori (RF). No izmeklētajiem pacientiem, vīriešiem bija lielāks vēdera apkārtmērs (VA) kā sievietēm (99,1 ± 13,6 cm pret 93,3 ± 15,2 cm), augstāks diastoliskais asinsspiediens (DAS) (83,6 ± 9,6 mmHG pret 81,8 ± 9,6 mmHG), augstāks glikozes (5,73 ± 1,4 mmol/L pret 5,49 ± 1,3 mmol/L) un triglicerīdu (TG) (1,89 ± 1,3 mmol/L pret 1,60 ± 1,0 mmol/L) līmenis, bet zemāks kopējā holesterīna (KH) (5,54 ± 1,2 mmol/L pret 5,79 ± 1,2 mmol/L) un augsta blīvuma lipoproteīnu (ABLH) (1,21 ± 0,4 pret 1,44 ± 0,4 mmol/L) līmenis. Salīdzinot jaunāko pacientu grupu (t.i. vīrieši < 55 gadiem un sievietes <65 gadiem) ar vecāko pacientu grupu, vecākajiem bija lielāks VA (98,4 ± 14,2 cm pret 92,8 ± 15,1 cm), augstāks sistoliskais asinsspiediens (SAS) (144,2 ± 19,2 mmHg pret 131,6 ± 18,5 mmHg), augstāks DAS (84,5 ± 8,8 mmHg pret 80,9 ± 9,8 mmHg), augstāks glikozes līmenis (5,74 ± 1,3 mmol/L pret 5,46 ± 1,3 mmol/L) un augstāks zema blīvuma lipoproteīnu holesterīna (3,68 ± 1,0 mmol/L pret 3,52 ± 1,0 mmol/L) līmenis, bet zemāks ABLH līmenis (1,3 ± 0,4 mmol/L pret 1,41 ± 0,4 mmol/L). Vecums ticami korelēja ar visiem riska faktoriem izņemot C-reaktīvo olbaltumu. Pētījums parādīja to, ka katrai vecuma un abu dzimuma grupām ir atšķirīgi dominējošie riska faktori, un to ietekmes novēršanai mazināšanai nepieciešamas atšķirīgas pieejas.

proceedings of the latvian academy of sciences. section b, natural sciences/latvijas zinātņu akadēmijas vēstis. a daļa, humanitārās un sociālās zinātnes