English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Summary Squamous cell carcinoma is the cause in most cases of cervical cancer. A very unusual subtype of squamous cell carcinoma is lymphoepithelioma-like carcinoma, found in less than 1% of the neoplasm processes in the uterine cervix. Histologically it looks like a large nest of big-sized tumor cells with large vascular nuclei. Immunohistochemical markers used for LELC are p63, p16, human leukocyte antigen-D related (HLA-DR), and B-cell lymphoma 2. Even though it has aggressive morphological features, it has a better prognosis than most carcinoma cases of the uterine cervix. The condition is treatable, with a hysterectomy and bilateral salpingo-oophorectomy as the most common method. There are rare cases of pelvic lymph node dissection reported in the literature. There is data that lymphoepithelioma-like carcinoma is associated with the Ebstein-Barr virus and human papillomavirus. According to a survey by Tseng et al. and Chao et al., EBV is associated with LELC in Asian women, while HPV is associated with Caucasian women. Due to the small number of studies found in the literature, no conclusion can be drawn concerning the said viruses’ involvement in Asian and Caucasian patients.

Presence of EBV and HPV Infection in Lymphoepithelioma-Like Carcinoma in the Uterine Cervix