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Malaria is an infectious disease caused by Plasmodium sp involving female anopheles masquitos during its transmission. Jung rahab (Bruckea frutescens L) was already known to have antimalaria activities in suppressing Plasmodium falciparum growth. The aim of this research is to find out antimalaria activity based on β-hematin inhibition and chemical separation of jung rahab water extract. This research was conducted through several steps, water extraction of jung rahab leaves, column chromatography, column fractions antimalarial screening, preparative TLC and compound identification using FTIR and GCMS. Results of this research showed that compound that has antimalarial activity based on FTIR and GCMS spectra was caryophyllene.

Aktivitas Antimalaria Berbasis Penghambatan β-Hematin dalam Ekstrak Air Daun Jung Rahab (Baeckea frutecens L)