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The international debate on animal testing, its improvement through the well known "3Rs" methodology, and the possibility of its replacement with the emergent NATs (Non-Animal Technologies) brought into the new millennium a turn. Nations as U.S.A. and U.K., and partly international bodies as the EU. seem be doing a renewed effort to diminish and possibly replace animal testing with more reliable and less invasive techniques, to which also the giants of the chemical and pharmaceutical industry seem very interested.

Both for Ethics and Health. Non-Animal Technologies: an achievable goal