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Objectives: To identify the prevalence of Barrett’s esophagus (BE) in patients with nasopharyngeal reflux (NPR) presenting to a tertiary rhinology practice in 2017, and to assess for any correlation with the presence of symptomatic gastroesophageal reflux disease (GERD). Methods: Demographic data, self-reported symptoms and relevant past medical history were compiled from a standardized intake questionnaire. Symptoms were grouped into 3 categories: NPR, laryngopharyngeal reflux (LPR) and GERD. Descriptive and nonparametric statistical analyses were performed. Results: Out of 807 new patients seen in 2017, 86 (10.7%) were referred to gastroenterology (GI) with NPR-associated symptoms, based on pre-existing referral indications. Forty-three patients were evaluated by a gastroenterologist, and 25 underwent EGD with pathology report available for review. BE was identified in 6/25 (24%) patients. Five of these six patients (83.3%) reported either mild or no GERD symptoms. No patient factors or presenting symptoms were significantly associated with the diagnosis of BE. Conclusions: This data in consecutive new patients suggests that compliance with referral recommendations is poor among NPR patients and that the incidence of BE in this population may be higher than that generally reported among GERD patients. This experience strengthens indications for referral for EGD to rule out BE, and it highlights the importance of patient education to improve compliance.

Nasopharyngeal Reflux: A New Indication for Esophagogastroduodenoscopy to Rule Out Barrett's Esophagus?