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A total of 136 mg of alkaloidal extract from leaves and 70 mg from stems of the endemic plant Faujasiopsis flexuosa (Lam) C. Jefrey subsps. bourbonensis C. Jefrey (syn. Faujasia flexuosa (Lam) Baker var. subcordata Cordem) growing on Réunion island was investigated for their content of pyrrolizidine alkaloids. The plant is used traditionaly against dysentery, diabetes and asthma. Our investigation showed that fourteen pyrrolizidine alkaloids are contained in F. flexuosa. Two of them (senecionine and seneciphyline) show toxic side-efects. Therefore, medical preparations from this plant should only be used under strong restrictions. Abbreviations: PAs: Pyrrolizidine Alkaloids; ASE: Accelerated Solvent Extraction

journal of natural and ayurvedic medicine

Pyrrolizidine Alkaloids from Faujasiopsis flexuosa (Lam.) C. Jeffrey subsp. bourbonensis C. Jeffrey (syn. Faujasia flexuosa (Lam) Baker var. subcordata Cordem)