English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Schatz, Robert Alfred. Ph. D., University of Rhode Island, June, 1972. Pargyline, Succinic Acid and L-Ascorbic Acid as Protective Agents Against Hyperbaric Oxygen Toxicity: Possible Involvement of Altered GammaAminobutyric Acid and Ammonia Metabolism . The mechanisms whereby pargyline, succinic acid and ascorbic acid protect againot hyperbaric oxygen convulsions, pulmonary damage and mortality follo~ing hyperbaric oxygen exposure were investigated in rel ation to the effects of these agents on hyperbaric oxygeninduced alterations in brain gamma-aminobutyric acid and ammonia metabolism . Exposure to hyperbaric oxygen (60 pounds per square inch, gauge pressure) produced convulsions, post-exposure lethality and elevation in lung weight, lung water content and lung hemoglobin content . Pargyline, succinic acid and ascorbic acid provided part:i.?.l protection against al l of the above aspects of oxygen toxicity. Comparison of the doses of pargyline , s~cc inic acid and ascorhic acid that provid8d maximal protect i on against hyperbaric oxygen convulsions shewed that aJ. l three agents were approximately equal , in the doses used, with respect to their effectiveness in decreasing the incidence of hyperbaric oxygen convulsions and increas ing the latency to their onset. Pargyli>le and succinic acid \·?ere approximately equal, in th e doses used, in their ability to reduce post-exposure lethality and hyperbaric oxygen-induced increases in lung weight , water content and hemoglobin content. Ascorbic acid was less effective in its ability to reduce the above changes induced by hyperbaric oxygen exposure.

PARGYLINE, SUCCINIC ACID AND L-ASCORBIC ACID AS PROTECTIVE AGENTS AGAINST HYPERBARIC OXYGEN TOXICITY: POSSIBLE INVOLVEMENT OF ALTERED GAMMA-AMINOBUTYRIC ACID AND AMMONIA METABOLISM