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We report an unusual case of pleomorphic adenoma with multifocal stromal bone formation, occurring in the upper lip of a 44-year-old Japanese woman. Islands of fibrous bone were in direct contact with stromal fibrocytes and parenchymal epithelial cells. A review of the literature revealed that stromal bone formation in pleomorphic adenoma of minor salivary gland origin is exceedingly rare.

Stromal Bone Formation in Pleomorphic Adenoma of Minor Salivary Gland Origin.