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Strains of Lactococcus lactis subsp. cremoris are used to produce yogurt containing exopolysaccharides with a sticky texture. When strain G3-2 producing exopolysaccharides was grown at elevated temperatures, a spontaneous mutant EPSC, which had lost exopolysaccharides biosynthesis, was isolated. Genomes of the two strains were determined to be composed of a 2.4-Mb chromosome and up to eleven plasmids, and it was revealed that one of the plasmids encoding the gene cluster for exopolysaccharides biosynthesis was lost selectively in EPSC.

journal of general and applied microbiology

Genome sequences of two strains of &lt;i&gt;Lactococcus lactis&lt;/i&gt; subsp. &lt;i&gt;cremoris&lt;/i&gt; with the same ancestry but a different capacity to produce exopolysaccharides