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A large increase in the number of arthroplasties performed worldwide during the last decade has resulted in improvement in the quality of life for thousands of patients. However, a small percentage of these patients are bound to exhibit some complication and be subjected to revision. One of the most dangerous complications is periprosthetic joint infection (PJI), involving the implant joint and periprosthetic tissues. Though the PJI cases’ percentage is small, their absolute number is significant and tends to further increase. PJI prolongs hospitalization, increases mortality rate and greatly degrades the patients’ quality of life, resulting in huge social and economic costs. For many years, timely diagnosis has been of great interest to clinical and laboratory doctors, in order to establish a common approach for immediate diagnosis and treatment, to the great patients’ benefit.

Application of the orthopedic implant sonication method to diagnosis of periprosthetic joint infections