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Colorectal cancer (CRC) is a malignant neoplasm with major impact on health today. There is, however, an efficient method for prevention and screening, which varies in different protocols according to each institution or country.  Objective : To evaluate the mortality rate and the economic cost of CRC in Brazil during the first 16 years of the 21st century.  Method : A retrospective, temporal aggregation study was conducted with an exploratory, documentary quantitative approach on CRC mortality from 2000 to 2016, based on the Mortality Information System database provided by the Brazilian Ministry of Health.  Results : In the study period, 218,000 deaths due to CRC were recorded. The CRC mortality rate was 6.2 (95% confidence interval, 5.59-6.81) per 100,000 population, with no significant difference between men and women. Of the 17 age subgroups analyzed, eight had a significant increase from 2000 to 2016, including all subgroups aged over 50 years.  Conclusion : There was an increase in mortality due to CRC in the study period.Keywords : Mortality; colorectal cancer; Brazil

Reported mortality for colorectal cancer in Brazil in the first 16 years of the 21st century