English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: Nowadays, although Negative Pressure Wound Therapy’s (NPWT) efficacy on healing wounds is widely known, it still has limited applications on infected wounds. Meanwhile, silver-containing foam dressings have been used for infected wounds ever since silver established a notable place in the material industry for its antibacterial properties. In this study, we design an experiment to investigate quantitatively the efficacy of silver-coated dressing materials and its antibacterial effects. Methods: We prepared a NPWT device with silver-coated foam (Curavac) and freeze-dried standard laboratory strains that are common wound pathogens: S. aureus (ATCC 25923), methicillin-resistant S. aureus (KCTC 3881), E. coli (KCTC 2571) and P. aeruginosa (KCTC 2513) bacteria and bouillon cul ture-medium, which were provided by the Hospital Microbiology laboratory. All reagents were used as-is without further purifications. Each pathogen was divided into five groups: 1) control, 2) pathogen with conventional pore foam (without pressure), 3) pathogen with silver-coated foam (without pressure), 4) pathogen with conventional pore foam (with pressure), and 5) pathogen with silver-coated foam (with pressure). The number of bacterial colo nies in each agar plate was evaluated after 72 hours by applying dressings and measuring inhibition zones. Results: The number of bacterial colonies of the a silver-coated foam group was significantly lower than the control group except one pathogen (E. coli) without pressure, and the bacterial colonies of silver-coated foam were significantly lower in all pathogen groups with pressure. Conclusion: This study demonstrated that the antibacterial effects of silver-coated dressing materials using quantitative analysis. Severely injured patients often develop wound infections, for which there is no obvious therapeutic approach yet. This study can suggest a novel wound management tool for such patients while also expecting to achieve faster surgical intervention with definite antibacterial effects.

A Novel Wound Management Strategy with Silver-coated Vacuum Dressing on Infected Wound: In Vitro Study