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Gallstones are a disease that is commonly found in Indonesian. Analysis of the composition of gallstones is important to determine the etiology, the metabolic basis of its formation, risk factors, and to educate for the patient's diet. The composition of gallstones can be influenced by various factors including age and sex. Until now there is no data analysis of the composition and distribution of gallstones in Jakarta. Thus, this study aims to analyze the composition and distribution of gallstones that are associated with age and sex. This study is a cross-sectional study using 230 secondary data from the analysis of the composition of gallstones in the Laboratory of Biochemistry and Molecular Biology of FMUI in the last 3 years period (2017 2019). Stone analysis was carried out with the Salkowski test to assess cholesterol and also calcium, carbonate, Fe, bile pigment, and phosphate assays. The results showed that 1.3% gallstones were pure stones and 98.7% were mixed stones. The most composition in mixed stones is cholesterol (83.91%). Gallstones are most commonly found in women in the age group of 40-49 years (27%). There is a correlation between cholesterol composition with age (p <0.05) but there is no relationship (p> 0.05) with gender (p> 0.05). This study concluded that cholesterol was the most common constituent of gallstone. Its levels increased with age and did not differ significantly between genders.

Analisis Komposisi dan Distribusi Batu Empedu di Laboratorium Fakultas Kedokteran Universitas Indonesia (FKUI) Jakarta