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The production of good replacement heifers is essential to maintain a high production level in a dairy herd. Incidences of diarrhoea and respiratory diseases significantly decrease heifer growth in terms of height and weight (Heinrichs and Heinrichs, 2011). Additionally, diseases in the preweaning period have a significant effect on production during the first lactation. In meta-analyses by Soberon and Van Amburgh (2013) and Gelsinger et al. (2016) it was found that milk production during the first lactation is increased by 130–155 kg of milk for every extra 100 g of weight gain per day in the preweaning period. High morbidity also increases veterinary, feed and labour costs. ABSTRACT. The study aimed to investigate the effects of a yeast/lactobacillus product, ‘ZooLac Bovimix Milk’, on the performance and health of Jersey heifer calves during the first month of life. The product contained live yeast (Saccharomyces cerevisiae) and postbiotic from Lactobacillus acidophilus. Danish Jersey heifer calves (n = 148) at birth were randomly allocated to a control diet (CON; 76 calves) or a diet supplemented with the yeast/lactobacillus product in the milk replacer (PRO; 72 calves). The average birth weight was 25.5 ± 0.3 kg and 25.4 ± 0.3 kg for CON and PRO groups, respectively. The yeast/lactobacillus product constituted 0.7% dry matter (DM) of the milk replacer for PRO group. Faecal samples were collected from 40 calves of each treatment around days 6–8 and 25–28, while blood was sampled from all calves around days 2–4 and 26–28. Additionally, 30 other faecal samples were obtained from some calves treated for diarrhoea. Significantly higher growth performance was observed in PRO group animals than in CON group ones, while no effect was found in the number of antibiotic treatments. The DM-% in manure from PRO group tended to be higher than for CON. Causative agents of diarrhoea were either Cryptosporidium spp., rotavirus A or both. Serum metabolites were unaffected by the treatment, however CON group tended to have a higher IgA level. Thus, supplementation of the yeast/lactobacillus product into the milk replacer during the first month of life had a positive effect on calf growth performance but did apparently not affect the overall health. Received: 22 June 2020 Revised: 17 August 2020 Accepted: 16 September 2020

journal of animal and feed sciences

The effects of supplementation of yeast (&lt;i&gt;Saccharomyces cerevisiae&lt;/i&gt;) and postbiotic from &lt;i&gt;Lactobacillus acidophilus&lt;/i&gt; on the health and growth performance of young Jersey heifer calves