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Aims: This sudy aims to determine the effect infusion of green tea (Camellia sinensis) to the renal histopathology picture of male white rats (Rattus norvegicus) Sprague dawley strain ethanol-induced. Methods: This study used 30 rats divided into 5 groups. The negative control (K-) was given distilled water 2 mL/day, the positive control (K +) was given ethanol 2 mL/day, the treatment group (P1, P2, P3) was given ethanol 2 mL and green tea infusion with respective doses of 0.375, 0.75 and 1.5 grams orally for 14 days. Then the renal retrieval is done to be examined microscopically. Results: The mean kidney damage score obtained was K= 0.36; K + = 3.24; P1 = 2.52; P2 = 2,4; and P3 = 2.2. Data analysis with One Way Anova Test and continued with Pos Hoc and found significant differences in Kto K+, P1, P2, P3; K+ is significant to K-, P1, P2, P3; and P1, P2, P3 are significant to K& K+. Conclusion: There is an effect of infusion of green tea (Camellia sinensis) on the renal histopathological picture of male white rats (Rattus norvegicus) ethanol-induced Sprague dawley strain.

journal of drug delivery and therapeutics

The Influence of Green Tea Infusion (Camellia sinensis) on Renal Histopathological Overview of Male White Rats (Rattus Norvegicus) Sprague Dawley Strain Induced by Ethanol