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A continuous cyclic voltammetric study of exemestane at glassy carbon electrode was carried out. The exemestane gives one well-defined reduction peak in the potential range -0.7 V to -0.8 V (Ag/Agcl) reference electrode in Britton Robinson buffer (BR) of pH 7.0.Under these conditions, a linear response was obtained between 4.7 x 10 M and 1.0 x 10 M in nonaqueous media for various voltammetric techniques. Moreover, the drug was analysed using Square Wave Cathodic adsorptive stripping voltammetry (SWCAdSV). Each determination method was fully validate and applied for the analysis of anti-cancer drug exemestane in its pharmaceutical dosages form. The influences of the pH, concentration, scan rate, volume of MWCNTs suspension, accumulation potential and time on peak current and peak potentials were examined.

international journal for research in applied science and engineering technology

Electrochemical Study of Anti-Cancer Drug Exemestane in Pharmaceutical Formulation by Voltammetric Techniques Using Multiwalled Carbon Nanotubes Modified Glassy Carbon Electrodes