Open AccessRole of β3 Integrin in Acute Renal Allograft Rejection in Humans
Author(s) -
Arun Chandrakantan,
David H. McDermott,
Hoanh Tran,
Mollie Jurewicz,
Lorenzo Gallon,
Robert S. Gaston,
Edgar L. Milford,
Reza Abdi
Publication year - 2007
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.01380307
Subject(s) - medicine , genotype , integrin , immunology , pathogenesis , urinary system , gastroenterology , gene , biology , receptor , genetics
Beta3 Integrin may play a role in the process of acute rejection by increasing leukocyte adhesion to the endothelium, cytotoxic T lymphocyte activation, and platelet aggregation.