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Helminths infections through the ability to stimulate the proliferation of regulatory T cells have been reported to affect the clinical manifestations of allergy. Besides Interleukin (IL)-10, Transforming Growth Factor (TGF)-β is cytokine released by regulatory T cells. This study is aimed to examine the effect of helminths infection on atopic dermatitis (AD) occurrence through TGF-β. This study was conducted in several teaching hospitals of Medical Faculty Hasanuddin University. Atopic dermatitis (AD) was diagnosed by using William criteria, the presence and severity of helminths infections were examined by Kato Katz methods, and serumTGF-β levels were measured by ELISA methods. A total of 80 children ranging from 2 to 7 years old participated in this study. The participants were divided into DA group(30 children) and non DA group (50 children). The percentage of helminths infection was 21,2% (17/80) with light infection intensity. Helminths infection did not affect TGF-β levels and the occurrence of AD. This study concludes that light intensity of helminths infection did not affect the levels of TGF-β as well as the occurrence of AD in children in Makassar.

Infeksi Cacing Tidak Berpengaruh terhadap Kadar Transforming Growth Factor (TGF)-Î² dan Kejadian Dermatitis Atopik pada Anak